Good morning. It’s September 17th, and the anniversary of the Battle of Antietam in 1862, the single bloodiest day in American history.

Your biggest battle? High-fructose corn syrup. And you don’t need a bayonet…just some fiber and the bravery to walk past the office donut box!

The rundown for this week:

  • ⌚ Apple Watch 11 has arrived

  • 😴 Eight Sleep scores $100MM

  • 👩🏻‍🔬 OpenAI set to begin first human trial

  • 🧬 Mitochondria used to fight cancer

Let’s get to it. 👇

Martha Stewart - The 8 best drinks to support healthy aging, according to nutritionists. (Read more)

Fierce Healthcare - The sleep tech industry is booming. Eight Sleep nabs $100MM to expand AI-powered research and development. (Read more)

Vanity Fair - A $160K longevity chamber is just one of the tricks utilized by elite athletes. Here’s an inside look. (Read more)

Realtor.com - The rapid rise of biohacking amenities in home buying, and whether these investments will pay off. (Read more)

Newsweek - Can’t sleep? Memory loss and faster brain aging might follow. (Read more)

PR Newswire - Lifeway unveils “Muscle Mate”, a ready-to-drink product pairing protein, creatine, and probiotic cultures. (Read more)

IN THE NEWS

Apple Watch 11 Announced: Guardian On Your Wrist

We’re not the biggest fans of strapping an entire computer to your wrist, but when a 3 trillion dollar company drops their latest wearable, we listen up.

Apple’s newest Watch release, announced on September 9th, puts health front and center, with some meaningful upgrades that go beyond step counts and calorie burn.

The standout feature is hypertension notifications. Using the optical heart sensor and a new algorithm, the Watch can flag potential high blood pressure trends over time, giving wearers a heads-up to check in with their doctor before issues escalate.

Sleep tracking also gets smarter.

A new Sleep Score breaks down quality and duration, giving a clearer picture of how restorative your rest actually is. Apple is also layering in broader health monitoring: wrist temperature tracking, ovulation estimates, and alerts for possible sleep apnea.

Perhaps the best part?

Many of these features are rolling out via the new watchOS, so you don’t necessarily need the newest hardware to get smarter health insights.

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IN THE NEWS

OpenAI & Retro Biosciences Tap AI-Models To Rewind The Clock

In spite of AI eliminating plenty of jobs and upending entire industries, the scientific community is welcoming the use to accelerate drug discovery.

Unveiled in their latest research paper, OpenAI and Retro Biosciences have shown that AI can radically accelerate one of the trickiest challenges in biology: reprogramming adult cells back into youthful stem cells.

By training a specialized model on protein structures, sequences, and evolutionary data, the teams designed brand-new versions of two reprogramming proteins, SOX2 and KLF4. The AI-born variants, dubbed RetroSOX and RetroKLF, didn’t just work—they outperformed nature by a staggering margin.

In lab tests, they boosted stem cell markers more than 50-fold compared to the originals, while also improving DNA repair along the way.

What’s remarkable is not just the result but the method: the AI didn’t settle for subtle edits, it ventured into bold redesigns with over 100 amino acid changes, creating proteins that no human would have guessed—and yet they worked seamlessly. That leap hints at a new era where algorithms don’t just analyze biology but invent it.

Next steps for OpenAI & Retro Bio: a first-of-its-kind human trial, set to launch in Q4-2025.

Mitochondria health is all the rage this year.

It’s as buzzy as NAD+ treatments, and peptides, with the research to back it up.

When your mitochondria are healthy, your body is a well-oiled, energy-boosting machine:

  • Higher energy production: Efficient mitochondria crank out more ATP, meaning your muscles, brain, and organs have the fuel they need to perform at their best.

  • Sharper cognition: Healthy mitochondria support better brain metabolism, improving memory, focus, and overall mental clarity.

  • Improved metabolic health: Strong mitochondria regulate blood sugar, burn fat more effectively, and reduce the risk of insulin resistance.

  • Lower inflammation & oxidative stress:Well-functioning mitochondria balance free radicals and antioxidants, protecting cells from damage and slowing aging.

  • Greater physical resilience:With robust energy production and repair systems, you recover faster from exercise, illness, or daily stressors.

When mitochondria aren’t working properly, a breeding ground for cancer can begin to surface:

  • More reactive oxygen species produced

  • Greater acidification

  • Worsened immune function

  • Improper cycle regulation

    and more…

But what if we could fight cancer with healthy mitochondria transplation?

Keep learning…👇🏼

KEEP READING

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