Good morning. It’s November 5 and we’re digesting the latest research drop on long-term use of melatonin for sleep. The TLDR; that purple gummy won’t save your sleep (or your heart) from the true crime marathons you’re binging each night.

The rundown for this week:

  • 📱Oasis App brings independent testing to the masses

  • 🧪 A breakdown of Alpha-GPC

  • 💰 Bryan Johnson takes on a who’s who of investors

  • 🍬 The dirty on artificial sweeteners

Let’s get to it. 👇

CNBC News - The 5 best fruits for immune support, from this leading Japanese nutritionist. (Read more)

New York Post - A-list celebrities like Jennifer Aniston & Gwyneth Paltrow are turning to this “beauty longevity” guru for help. Here’s their health stack: (Read more)

HuffPost - The best anti-aging skincare products ahead of holiday shopping season. (Read more)

MedicalExpress - USC researchers find that reducing reliance on sleep medications leads to improved quality of life (and longer). (Read more)

Newsweek - Catch the headline about “vaginal probiotic lollipops”? Here’s the breakdown: (Read more)

PR Newswire - ShapeScale launches first AI-driven 3D body scanner, offering true 97% DEXA-leval accuracy in under a minute. (Read more)

Blueprint - Bryan Johnson’s blueprint nabs $60M, bringing in an impressive list of celebrities, influences, and longevity investors. (Read more)

IN THE NEWS

Is Your Food Toxic? Check The Oasis App

Let’s be real. If you’re still buying products because of the pretty leaf on the package or some vague, aggressively capitalized promise about “HOLISTIC HEALTH,” bless your heart.

You’re probably being duped.

The entire consumer landscape is a cynical, multi-billion dollar effort to confuse us all into buying things that are mediocre at best, and actively detrimental at worst.

The head-turning lead-protein report was the tip of the iceberg, so if you’re thinking to yourself that other foods in your pantry might be secretly toxic, you might want to check out the Oasis app.

Oasis runs independent testing across virtually every single food & beverage category, exposing the truth behind claims and ambiguous nutritional labels.

Here’s a quick breakdown of how it works:

  • Compositional Integrity (Purity): Does the product have any bad stuff? This is the most crucial step, where Oasis screens for hidden contaminants like heavy metals, microplastics, pesticides, and unnecessary chemical additives that basic regulations often miss.

  • Funtional Efficacy (Performance): Does the product actually work as claimed? For supplements, they check if the body can truly absorb the ingredients (bioavailability). For filters and purifiers, they verify that the technology performs effectively and removes the specific pollutants it promises to.

  • Scientific Transparency (Trust) Can the brand back up its claims? This ensures the product's benefits are supported by legitimate, peer-reviewed science, and the company is fully transparent about where its ingredients are sourced.

The final score is not a user review average, but a scientifically validated metric that tells you instantly if a product is truly high-quality, safe, and effective. It's the ultimate tool for making smart, evidence-based purchases.

You know you’re doing something right when a bottled water company sends a Cease & Desist letter after being exposed for arsenic in the water.

TOGETHER WITH CBDistillery

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FROM THE CLINIC

🧠 Biohacking Your Brain: The Rise of Alpha GPC

Today, we're pulling back the curtain on Alpha-GPC, the compound that's often misunderstood but might hold the key to your cognitive ceiling. Unlike many trendy compounds, A-GPC has been studied extensively in clinical settings, particuarly concerning age-related cognitive decline.

It doesn't just trickle into your system; it floods your brain with the raw material needed for memory formation, muscle control, and deep focus.

Let’s back it up and start from the top…

What is Alpha GPC?

Alpha-GPC is a naturally occurring choline compound found in the brain, but it’s often synthesized for supplement form. It’s essentially a highly bioavailable choline donor, meaning your body absorbs it quickly and efficiently.

Once ingested, Alpha-GPC crosses the protective blood-brain barrier to deliver a crucial component: choline.

Choline is the direct precursor to a powerful neurotransmitter called acetylcholine. Think of acetylcholine as the primary messenger for learning, memory, attention, and muscle contraction. By delivering the raw material, Alpha-GPC effectively boosts the brain's supply, acting as fuel for your cognitive engine.

What does the science say?

Alpha-GPC's popularity has surged far beyond the niche biohacking community. It's now a staple in everything from high-end nootropic stacks (supplements designed to improve cognitive function) to performance-focused pre-workout blends. Athletes, CEOs, students, and anyone seeking a competitive edge are turning to it for a cleaner, non-stimulant boost.

Research provides compelling reasons for this mainstream embrace:

  • Cognitive Enhancement: Studies, particularly those involving individuals with age-related decline or vascular issues, have shown Alpha-GPC's ability to support memory, attention, and overall cognitive function. Promising acute trials in healthy young adults have also indicated improvements in tasks that measure focus and the ability to inhibit interference (like the Stroop test).

  • Physical Power Output: For athletes, the benefits extend to the gym. Alpha-GPC has been linked to increased peak force production and improved vertical jump power, likely due to its role in neuromuscular signaling—the efficient communication between your brain and muscles.

  • Motivation and Mood: Some human clinical trials suggest that daily Alpha-GPC supplementation can significantly increase motivation scores in healthy volunteers.

The real-world appeal of Alpha-GPC is its dual effectiveness.

Users report tangible wins: lightning-fast information processing and a noticeable capacity to activate muscles. To see these results, users typically stick to 300-600mg.

While A-GPC is well-studied and generally safe for most, you know the drill; ease into it, start small, and practice “responsible hacking”.

Want to dive deeper?

Researchers conducted a randomized, double-blind trial on 261 patients with mild-to-moderate Alzheimer's disease. Patients receiving A-GPC saw significant improvements in memory, attention, and cognitive function compared to the placebo group.

This should not be a suprise to anybody….but….

Are you a diet coke addict?

Or are you swapping out soda for drinks with artificial sweeteners?

You might want to pay attention to the mountain of evidence that says these are just as bad for your health over the long term as the nostalgic sugary treats from your childhood.

💡 Results from this study show that higher consumption of low- and no-calorie sweeteners (LNCSs) was generally linked to a faster decline in cognitive functions like verbal fluency and memory, especially in participants younger than 60 and regardless of diabetes status.

Keep reading…👇🏼

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