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We’ve long known that psilocybin, the psychoactive compound in so-called “magic mushrooms”, can bend perception and brighten moods.

But what if it could also slow down aging at the cellular level?

That’s the latest story behind a peer-reviewed study published in Nature Aging and Longevity, where researchers administered psilocin (the metabolized form of psilocybin) to aged mice and human cells.

And the results are the talk of the town. 🥳

Microdosing psilocybin is already trending in Silicon Valley and psychotherapy circles, but monthly dosing for longevity? A surprising extension in both cell lifespan and animal survival, without any obvious toxicity or behavioral side effects.

Researchers from Baylor, Emory, and other institutions set out to test whether psilocin (the active compound derived from psilocybin) could impact aging markers at the cellular and organism level.

In the lab, they treated human lung and skin fibroblast cells with two concentrations of psilocin (10 μM and 100 μM) to assess its impact on cell lifespan.

In parallel, they administered monthly injections of psilocybin or psilocin to aged mice (19 months old, roughly equivalent to 60 in human years) at doses of 5 mg/kg and 15 mg/kg over a 10-month period. Control groups received no psychedelic treatment.

Over 150 clinical studies have explored pscilocybin’s effects on depression, anxiety, addiction, and even Alzheimer’s.

But this time it’s different.

This is the first published evidence showing psilocin can extend lifespan at both cellular and whole-organism levels.

More research is needed in humans, but it’s a landmark moment in the crossover between psychedelics and aging research.

👉🏾 Take a closer look at the trial results.

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