Good morning. This is Stayinβ Alive, the space that helps you live with more pep in your step than Nicole Richie on an adderall binge.
The rundown for this weekβs edition:
β³ Longevity events heat up in March
π¬ Men with better semen quality are living the longest
ππ»ββοΈ VO2 max is the health metric youβve been missing
𧬠A key protein may unlock cell rejuvenation
Letβs get to it. π


Time Magazine - Mastering your balance; a hack you arenβt thinking about. (Read more)
News Medical Life Sciences - Men's semen quality is associated with how long they live, according to a study of nearly 80,000 men. (Read more)
Athletech - Life Time opens itβs 2nd location featuring the Miora Performance & Longevity Clinic in Chicago. (Read more)
MorningStar - upLift 5 releases itβs new at-home anti-aging beauty device, using NASA-inspired tech to reverse the signs of aging. (Read more)

March 13th | Miami, FL | Longevity Science Summit
The summit will feature a presentation from LongeVC, a venture capital fund supporting groundbreaking longevity and biotech companies.
March 25th | Miami, FL | Donβt Die Summit
A full day where youβll explore the newest therapies and technologies, and connect with like-minded individuals.
March 29-30 | Los Angeles, CA | Biohackers World
2-day conference & expo featuring wellness technologies of the future and immersive experiences

Combining omega-3s, vitamin D, and regular exercise may reduce biological aging far beyond the impacts of these interventions in isolation, a new study indicates.
Specifically, supplementing with omega-3s alone reduced biological age on several next-generation epigenetic clocksβ¦ x.com/i/web/status/1β¦
β #Dr. Rhonda Patrick (#@foundmyfitness)
9:11 PM β’ Feb 11, 2025
π€― BTWβ¦ π€―
Itβs been 5 FULL YEARS since the world went into covid lockdown in March 2020β¦


STORY OF THE WEEK
Osaka Study Delivers Breakthrough In Anti-Aging Research
A recent discovery at Osaka University in Japan has offered a glimpse into the possibility of genuinely reversing the aging process at a cellular level.
The research focuses on the intricate dance of cellular senescence, the process by which cells lose their ability to divide and contribute to tissue repair, becoming what are often termed "zombie cells." These senescent cells accumulate with age, releasing inflammatory molecules that contribute to age-related decline and disease.
What sets this Osaka University study apart is its exploration of a novel method to selectively eliminate these senescent cells, not just halting their harmful effects, but potentially rewinding the cellular clock.
While previous research has explored senolytics, drugs that target senescent cells, this study suggests a more precise and potentially more effective approach. By targeting a specific protein, researchers may be able to minimize off-target effects and maximize the elimination of harmful senescent cells.


DEEP DIVE SESSION
Why Your VO2 Max Matters More Than You Think
Weβve been hearing a A LOT about VO2 max, the unsung hero of longevity, the oxygen-guzzling gladiator of your cardiovascular system.
So letβs talk about it.
What is VO2 Max?
Well to start, some people are calling it the βmost important health metricβ.
VO2 max is the maximum amount of oxygen that your body can use during exercise. Itβs a measure of your cardiovascular fitness and is often used to assess your overall health.
And what does that translate into? A higher VO2 max means that you have a more efficient cardiovascular system and can better use oxygen to fuel your muscles.
Think of it as your bodyβs ability to turn air into pure, unadulterated βLFG π .β
And one more thing β you donβt need to run a marathon to reap the rewards. Even brisk walking, cycling, or swimming can nudge your VO2 max in the right direction.
So how Does VO2 Max Impact Longevity? π€
A number of studies have shown that a higher VO2 max is associated with a longer lifespan. In one study, researchers followed over 100,000 people for 25 years and found that those with a higher VO2 max were more likely to live longer.
Another study found that people with a higher VO2 max were less likely to die from heart disease, cancer, and other chronic diseases.
If you needed some motivation to get your cardiovascular health in order, then let this be your sign - its MAX SEASON.
Ditch the remote, lace up those sneakers, and get moving. Your lungs, and your future self, will thank you.



Weβve cut through the noise so you donβt have to.
Check out our March 2025 Top 25 list of the best conversations on all things longevity and health.

We know weβre not immortal.
But we can try.
Tell us what you think.
How'd you like this week's edition?
